Package: PPMR Title: Probabilistic Two Sample Mendelian Randomization Type: Package Version: 1.0 Authors@R: c( person(given = "Zhongshang", family = "Yuan", role = c("aut")), person(given = "Xiang", family = "Zhou", role = c("aut"), email = "xzhousph@umich.edu"), person(given = "Michael", family = "Kleinsasser", role = c("cre"), email = "mkleinsa@umich.edu")) Description: Efficient statistical inference of two-sample MR (Mendelian Randomization) analysis. It can account for the correlated instruments and the horizontal pleiotropy, and can provide the accurate estimates of both causal effect and horizontal pleiotropy effect as well as the two corresponding p-values. There are two main functions in the 'PPMR' package. One is PMR_individual() for individual level data, the other is PMR_summary() for summary data. License: GPL-3 Encoding: UTF-8 LazyData: true Imports: Rcpp (>= 1.0.0) LinkingTo: Rcpp, RcppArmadillo RoxygenNote: 6.1.1.9000 NeedsCompilation: yes BugReports: https://github.com/umich-biostatistics/PPMR/issues Packaged: 2026-06-19 06:51:59 UTC; root Repository: https://umich-biostatistics.r-universe.dev Date/Publication: 2019-08-08 13:40:48 UTC RemoteUrl: https://github.com/umich-biostatistics/ppmr RemoteRef: HEAD RemoteSha: 27e6c111671f693b90e01c5bb0d00ca8196809af Author: Zhongshang Yuan [aut], Xiang Zhou [aut], Michael Kleinsasser [cre] Maintainer: Michael Kleinsasser Depends: R (>= 3.5.0)