{ "_id": "6a5ef9bc9baadeef8ab580ab", "Package": "PPMR", "Title": "Probabilistic Two Sample Mendelian Randomization", "Type": "Package", "Version": "1.0", "Authors@R": "c(\nperson(given = \"Zhongshang\", family = \"Yuan\", role = c(\"aut\")),\nperson(given = \"Xiang\", family = \"Zhou\", role = c(\"aut\"), email = \"xzhousph@umich.edu\"),\nperson(given = \"Michael\", family = \"Kleinsasser\", role = c(\"cre\"), email = \"mkleinsa@umich.edu\"))", "Description": "Efficient statistical inference of two-sample MR\n(Mendelian Randomization) analysis. It can account for the\ncorrelated instruments and the horizontal pleiotropy, and can\nprovide the accurate estimates of both causal effect and\nhorizontal pleiotropy effect as well as the two corresponding\np-values. There are two main functions in the 'PPMR' package.\nOne is PMR_individual() for individual level data, the other is\nPMR_summary() for summary data.", "License": "GPL-3", "Encoding": "UTF-8", "LazyData": "true", "RoxygenNote": "6.1.1.9000", "NeedsCompilation": "yes", "BugReports": "https://github.com/umich-biostatistics/PPMR/issues", "Packaged": { "Date": "2026-07-19 09:21:23 UTC", "User": "root" }, "Repository": "https://umich-biostatistics.r-universe.dev", "Date/Publication": "2019-08-08 13:40:48 UTC", "RemoteUrl": "https://github.com/umich-biostatistics/ppmr", "RemoteRef": "HEAD", "RemoteSha": "27e6c111671f693b90e01c5bb0d00ca8196809af", "Author": "Zhongshang Yuan [aut],\nXiang Zhou [aut],\nMichael Kleinsasser [cre]", "Maintainer": "Michael Kleinsasser ", "_user": "umich-biostatistics", "_type": "src", "_file": "PPMR_1.0.tar.gz", "_fileid": "https://r2.ropensci.org/5976926c694dd8ce61072cb87f8edeeb46292ac7e3f5932a28f29224d0202076", "_filesize": 161876, "_sha256": "5976926c694dd8ce61072cb87f8edeeb46292ac7e3f5932a28f29224d0202076", "_expires": "2026-10-27T09:27:05.000Z", "_created": "2026-07-19T09:21:23.000Z", "_published": "2026-07-21T04:46:52.222Z", "_jobs": [ { "job": 88544888068, "time": 136, "config": "linux-devel-arm64", "r": "4.7.0", "check": "NOTE", "artifact": "8440713201" }, { "job": 88544888126, "time": 132, "config": "linux-devel-x86_64", "r": "4.7.0", "check": "NOTE", "artifact": "8440712081" }, { "job": 88544888212, "time": 131, "config": "linux-release-arm64", "r": "4.6.1", "check": "NOTE", "artifact": "8440712515" }, { "job": 88544888346, "time": 131, "config": "linux-release-x86_64", "r": "4.6.1", "check": "NOTE", "artifact": "8440711952" }, { "job": 88544887796, "time": 82, "config": "macos-oldrel-arm64", "r": "4.5.3", "check": "FAIL", "artifact": "" }, { "job": 88544887808, "time": 140, "config": "macos-oldrel-x86_64", "r": "4.5.3", "check": "FAIL", "artifact": "" }, { "job": 88544888478, "time": 93, "config": "macos-release-arm64", "r": "4.6.1", "check": "NOTE", "artifact": "8440706931" }, { "job": 88544888257, "time": 279, "config": "macos-release-x86_64", "r": "4.6.1", "check": "NOTE", "artifact": "8440732444" }, { "job": 88544887752, "time": 178, "config": "source", "r": "4.6.1", "check": "OK", "artifact": "8440693532" }, { "job": 88544888276, "time": 126, "config": "wasm-release", "r": "4.6.0", "check": "OK", "artifact": "8440711293" }, { "job": 88544888283, "time": 107, "config": "windows-devel", "r": "4.7.0", "check": "NOTE", "artifact": "8440708891" }, { "job": 88544887806, "time": 57, "config": "windows-oldrel", "r": "4.5.3", "check": "FAIL", "artifact": "" }, { "job": 88544888187, "time": 122, "config": "windows-release", "r": "4.6.1", "check": "NOTE", "artifact": "8440710955" } ], "_host": "GitHub-Actions", "_buildurl": "https://github.com/r-universe/umich-biostatistics/actions/runs/29681344269", "_status": "success", "_upstream": "https://github.com/umich-biostatistics/ppmr", "_commit": { "id": "27e6c111671f693b90e01c5bb0d00ca8196809af", "author": "Kleinsasser ", "committer": "Kleinsasser ", "message": "Changed package name and added standard formatting\n", "time": 1565271648 }, "_maintainer": { "name": "Michael Kleinsasser", "email": "mkleinsa@umich.edu", "login": "mkleinsa", "description": "R programmer for the Department of Biostatistics at the University of Michigan, Ann Arbor. M.S. Statistics. ", "uuid": 39565600 }, "_distro": "resolute", "_registered": true, "_dependencies": [ { "package": "R", "version": ">= 3.5.0", "role": "Depends" }, { "package": "Rcpp", "role": "LinkingTo" }, { "package": "RcppArmadillo", "role": "LinkingTo" }, { "package": "Rcpp", "version": ">= 1.0.0", "role": "Imports" } ], "_owner": "umich-biostatistics", "_selfowned": true, "_usedby": 0, "_updates": [], "_tags": [], "_stars": 2, "_contributors": [ { "user": "mkleinsa", "count": 15, "uuid": 39565600 } ], "_userbio": { "uuid": 51202056, "type": "organization", "name": "Department of Biostatistics at the University of Michigan", "followers": 22 }, "_downloads": { "count": 241, "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/PPMR" }, "_mentions": 1, "_devurl": "https://github.com/umich-biostatistics/ppmr", "_searchresults": 20, "_topics": [ "openblas", "cpp", "openmp" ], "_rbuild": "4.6.1", "_assets": [ "extra/citation.cff", "extra/citation.html", "extra/citation.json", "extra/citation.txt", "extra/contents.json", "extra/PPMR.html", "extra/readme.html", "extra/readme.md", "manual.pdf" ], "_homeurl": "https://github.com/umich-biostatistics/ppmr", "_realowner": "umich-biostatistics", "_cranurl": true, "_releases": [ { "version": "1.0", "date": "2019-08-09" }, { "version": "1.0.1", "date": "2025-09-17" } ], "_exports": [ "PMR_individual", "PMR_summary" ], "_datasets": [ { "name": "Exampleindividual", "title": "Individual level dataset", "object": "Exampleindividual", "class": [ "list" ], "fields": [], "table": false, "tojson": true }, { "name": "Examplesummary", "title": "Summary level dataset", "object": "Examplesummary", "class": [ "list" ], "fields": [], "table": false, "tojson": true } ], "_help": [ { "page": "Exampleindividual", "title": "Individual level dataset", "topics": [ "Exampleindividual" ] }, { "page": "Examplesummary", "title": "Summary level dataset", "topics": [ "Examplesummary" ] }, { "page": "PMR_individual", "title": "PMR model with individual level data", "topics": [ "PMR_individual" ] }, { "page": "PMR_summary", "title": "PMR model with summary data", "topics": [ "PMR_summary" ] } ], "_readme": "https://github.com/umich-biostatistics/ppmr/raw/HEAD/README.md", "_rundeps": [ "Rcpp", "RcppArmadillo" ], "_sysdeps": [ { "shlib": "liblapack", "package": "libopenblas0-pthread", "source": "openblas", "version": "0.3.32+ds-5", "name": "openblas", "homepage": "https://www.openblas.net/", "description": "Optimized BLAS (linear algebra) library (shared lib, pthread)" }, { "shlib": "libblas", "package": "libopenblas0-pthread", "source": "openblas", "version": "0.3.32+ds-5", "name": "openblas", "homepage": "https://www.openblas.net/", "description": "Optimized BLAS (linear algebra) library (shared lib, pthread)" }, { "shlib": "libstdc++", "package": "libstdc++6", "source": "gcc", "version": "16-20260322-1ubuntu1", "name": "c++", "homepage": "http://gcc.gnu.org/", "description": "GNU Standard C++ Library v3" }, { "shlib": "libgomp", "package": "libgomp1", "source": "gcc", "version": "16-20260322-1ubuntu1", "name": "openmp", "homepage": "http://gcc.gnu.org/", "description": "GCC OpenMP (GOMP) support library" } ], "_score": 3.3010299956639813, "_indexed": true, "_nocasepkg": "ppmr", "_universes": [ "umich-biostatistics", "mkleinsa" ], "_binaries": [ { "r": "4.5.3", "os": "mac", "version": "1.0", "date": "2026-04-20T07:38:34.000Z", "arch": "aarch64", "commit": "27e6c111671f693b90e01c5bb0d00ca8196809af", "fileid": "https://r2.ropensci.org/47a06846e91d4f2fdb1dbd3e8344af8b0e056a3a73b1dff15ed881dcb47b9109", "status": "success", "check": "NOTE", "buildurl": "https://github.com/r-universe/umich-biostatistics/actions/runs/24654211122" }, { "r": "4.5.3", "os": "mac", "version": "1.0", "date": "2026-04-20T07:39:48.000Z", "arch": "x86_64", "commit": "27e6c111671f693b90e01c5bb0d00ca8196809af", "fileid": "https://r2.ropensci.org/137baf7d1d9087996930413d609fa8ef640d7e60162d6ccd1fe3e96803ced331", "status": "success", "check": "NOTE", "buildurl": "https://github.com/r-universe/umich-biostatistics/actions/runs/24654211122" }, { "r": "4.5.3", "os": "win", "version": "1.0", "date": "2026-04-20T07:38:37.000Z", "arch": "x86_64", "commit": "27e6c111671f693b90e01c5bb0d00ca8196809af", "fileid": "https://r2.ropensci.org/713767b7a313d63bee5a2f6b95adcce7b74dc1a0e97ae97c41a1178758b5e4ae", "status": "success", "check": "NOTE", "buildurl": "https://github.com/r-universe/umich-biostatistics/actions/runs/24654211122" }, { "r": "4.7.0", "os": "linux", "version": "1.0", "date": "2026-07-19T09:23:56.000Z", "distro": "resolute", "arch": "aarch64", "commit": "27e6c111671f693b90e01c5bb0d00ca8196809af", "fileid": "https://r2.ropensci.org/a31104c92f1a1721949c0d10591cb497ac4a822d58f630703dc6f5904f45122a", "status": "success", "check": "NOTE", "buildurl": "https://github.com/r-universe/umich-biostatistics/actions/runs/29681344269" }, { "r": "4.7.0", "os": "linux", "version": "1.0", "date": "2026-07-19T09:23:48.000Z", "distro": "resolute", "arch": "x86_64", "commit": "27e6c111671f693b90e01c5bb0d00ca8196809af", "fileid": "https://r2.ropensci.org/5ed1e4ec678ee123f9be46f35967353bc137af15f9de1469dc1ea1a379b9f918", "status": "success", "check": "NOTE", "buildurl": "https://github.com/r-universe/umich-biostatistics/actions/runs/29681344269" }, { "r": "4.6.1", "os": "linux", "version": "1.0", "date": "2026-07-19T09:23:50.000Z", "distro": "resolute", "arch": "aarch64", "commit": "27e6c111671f693b90e01c5bb0d00ca8196809af", "fileid": "https://r2.ropensci.org/0ab4855e7f25ce58cf25b7f03a2095d88300e68023d1fa9e24ec9ab5b20d3245", "status": "success", "check": "NOTE", "buildurl": "https://github.com/r-universe/umich-biostatistics/actions/runs/29681344269" }, { "r": "4.6.1", "os": "linux", "version": "1.0", "date": "2026-07-19T09:23:39.000Z", "distro": "resolute", "arch": "x86_64", "commit": "27e6c111671f693b90e01c5bb0d00ca8196809af", "fileid": "https://r2.ropensci.org/6c56913cab179ae00567c71b2177b3b5429ef23a550f1b3d7db33bd7eec62084", "status": "success", "check": "NOTE", "buildurl": "https://github.com/r-universe/umich-biostatistics/actions/runs/29681344269" }, { "r": "4.6.1", "os": "mac", "version": "1.0", "date": "2026-07-19T09:23:13.000Z", "arch": "aarch64", "commit": "27e6c111671f693b90e01c5bb0d00ca8196809af", "fileid": "https://r2.ropensci.org/55dbb36cd390e194475197255d051b55285fa67ed413a3307e706fa195e60414", "status": "success", "check": "NOTE", "buildurl": "https://github.com/r-universe/umich-biostatistics/actions/runs/29681344269" }, { "r": "4.6.1", "os": "mac", "version": "1.0", "date": "2026-07-19T09:26:00.000Z", "arch": "x86_64", "commit": "27e6c111671f693b90e01c5bb0d00ca8196809af", "fileid": "https://r2.ropensci.org/5fad766d71a6b422785ef9c9bcaf604a8ec9f988cbc0f19278775d5462811864", "status": "success", "check": "NOTE", "buildurl": "https://github.com/r-universe/umich-biostatistics/actions/runs/29681344269" }, { "r": "4.6.0", "os": "wasm", "version": "1.0", "date": "2026-07-19T09:23:48.000Z", "arch": "emscripten", "commit": "27e6c111671f693b90e01c5bb0d00ca8196809af", "fileid": "https://r2.ropensci.org/b5d1c71c3dca59ad8fd49b6c17b037574a776400eff137029cb95d660da589e9", "status": "success", "buildurl": "https://github.com/r-universe/umich-biostatistics/actions/runs/29681344269" }, { "r": "4.7.0", "os": "win", "version": "1.0", "date": "2026-07-19T09:22:45.000Z", "arch": "x86_64", "commit": "27e6c111671f693b90e01c5bb0d00ca8196809af", "fileid": "https://r2.ropensci.org/01c3574bfc465c1db9bd326da85f8231969ff8716aedd1928af6f2254bcdb032", "status": "success", "check": "NOTE", "buildurl": "https://github.com/r-universe/umich-biostatistics/actions/runs/29681344269" }, { "r": "4.6.1", "os": "win", "version": "1.0", "date": "2026-07-19T09:23:02.000Z", "arch": "x86_64", "commit": "27e6c111671f693b90e01c5bb0d00ca8196809af", "fileid": "https://r2.ropensci.org/435e18244ba4c89770f871787a439561756a7271f76e26a5bbca62f512ab62b8", "status": "success", "check": "NOTE", "buildurl": "https://github.com/r-universe/umich-biostatistics/actions/runs/29681344269" } ] }